Cardiovascular diseases (CVDs) are the leading cause of death worldwide today, but are not just a modern phenomenon. To explore the deep roots of CVDs in human history, this book, for the first time, brings together bioarchaeological evidence from different periods, as old as 5000 BC, and geographic locations from Alaska to Northern Africa. Experts in their fields showcase the powerful tool set available to bioarchaeology, which allows a more comprehensive reconstruction of the human past through evidence for disease. The tools include aDNA and histological analyses and digital imaging techniques for studying skeletal and mummified human remains. The insights gained from these studies are not only of value to historical research but also demonstrate how the science of archaeological human remains can provide the long view of the history of disease and contributes to modern biomedical research within the context of evolutionary medicine.

Using human skeletal remains, this volume traces health, workload and violence in the European population over the past 2,000 years. Health was surprisingly good for people who lived during the early Medieval Period. The Plague of Justinian of the sixth century was ultimately beneficial for health because the smaller population had relatively more resources that contributed to better living conditions. Increasing population density and inequality in the following centuries imposed an unhealthy diet - poor in protein - on the European population. With the onset of the Little Ice Age in the late Middle Ages, a further health decline ensued, which was not reversed until the nineteenth century. While some aspects of health declined, other attributes improved. During the early modern period, interpersonal violence (outside of warfare) declined possibly because stronger states and institutions were able to enforce compromise and cooperation. European health over the past two millennia was hence multifaceted in nature.

Evolutionary medicine has been steadily gaining recognition, not only in modern clinical research and practice, but also in bioarchaeology (the study of archaeological human remains) and especially its sub-discipline, palaeopathology. To date, however, palaeopathology has not been necessarily recognised as particularly useful to the field and most key texts in evolutionary medicine have tended to overlook it. This novel text is the first to highlight the benefits of using palaeopathological research to answer questions about the evolution of disease and its application to current health problems, as well as the benefits of using evolutionary thinking in medicine to help interpret historical disease processes. It presents hypothesis-driven research by experts in biological anthropology (including palaeopathology), medicine, health sciences, and evolutionary medicine through a series of unique case studies that address specific research questions. Each chapter has been co-authored by two or more researchers with different disciplinary perspectives in order to provide original, insightful, and interdisciplinary contributions that will provide new insights for both palaeopathology and evolutionary medicine. Palaeopathology and Evolutionary Medicine is intended for graduate level students and professional researchers in a wide range of fields including the humanities (history), social sciences (anthropology, archaeology, palaeopathology, geography), and life sciences (medicine and biology). Relevant courses include evolutionary medicine, evolutionary anthropology, medical anthropology, and palaeopathology.

Through an unprecedented multidisciplinary and global approach, this book documents the dramatic several-thousand-year history of leprosy using bioarchaeological, clinical, and historical information from a wide variety of contexts, dispelling many long-standing myths about the disease. Drawing on her 30 years of research on the infection, Charlotte Roberts begins by outlining its bacterial causes, how it spreads, and how it affects the body. She then considers its diagnosis and treatment, both historically and in the present. She also looks at the methods and tools used by paleopathologists to identify signs of leprosy in skeletons. Examining evidence in human remains from many countries, particularly in Europe and including Britain, Hungary, and Sweden, Roberts demonstrates that those affected were usually buried in the same cemeteries as their communities, contrary to the popular belief that they were all ostracized or isolated from society into leprosy hospitals. Other myths addressed by Roberts include the assumptions that leprosy can't be cured, that leprosy is no longer a problem today, and that what is called "leprosy" in the Bible is the same illness as the disease with that name now. Roberts concludes by projecting the future of leprosy, arguing that researchers need to study the disease through an ethically grounded evolutionary perspective. Importantly, she advises against use of the word "leper" to avoid perpetuating stigma today surrounding people with the infection and resulting disabilities. Leprosy will stand as the authoritative source on the subject for years to come. A volume in the series Bioarchaeological Interpretations of the Human Past: Local, Regional, and Global Perspectives, edited by Clark Spencer Larsen.

Thirty-seven papers, from a conference held in Bradford in 1999, examine leprosy from all angles: as a historical disease overwhelmed by stigma and as a condition that is still prevalent in much of the world despite new medications. Contributors discuss the medical diagnosis and treatment of leprosy, its effects on the skeleton using archaeological and historical evidence, its occurrence in the archaeological record worldwide and detecting its traces in DNA. Case studies are taken from across the ancient, medieval and modern worlds, including the Near East, Roman Egypt, medieval England, Wales and Ireland, Eastern Europe, Scandinavia, Asia and the Pacific.

Tuberculosis has plagued humans and animals for thousands of years. Though apparently in decline with the advent of effective chemotherapy and improved living conditions, sanitation, and diet during the first half of the 20th century, TB has reawakened in both developed and developing countries, particularly among susceptible populations with immunodeficiency disorders. These authors offer a detailed study of the history of this persistent and important infectious disease, covering its etiology, epidemiology, and pathogenesis. Beginning with a discussion of the epidemiology, clinical signs and symptoms of tuberculosis, and skeletal changes associated with it, Roberts and Buikstra examine evidence for the disease through time in both human and nonhuman populations. They devote particular attention to the paleopathological evidence of tuberculosis throughout human history found in both Old and New World archaeological sites. With a review of the hard evidence of tuberculosis from the archaeological record (skeletons showing evidence of the disease), they focus on how and why the disease developed in antiquity, its evolutionary routes, and how past populations treated it. The authors augment clinical data with evidence from a variety of sources including art and documentary materials. A concluding chapter addresses the current reemergent status of the disease and its future prospects. The authors reveal that tuberculosis has repeatedly increased over time as societies have become more complex socially, economically, and politically. Their detailed presentation of the clinical data on tuberculosis and its many causative factors brings together information from a wealth of sources worldwide and mounts an argument rich in paleoepidemiological and historical data that challenges accepted dogma about the conquest of TB by modern technology. Their account will be of interest to anthropologists, archaeologists, biologists, and sociologists as well as clinicians and medical historians.